"Develop an attitude of gratitude, and give thanks for everything that happens to you, knowing that every step forward is a step toward achieving something and better than your current situation." …….Brian Tracy Words are not enough to thank my guide I take this opportunity to acknowledge the guidance and encouragement of my guide Dr. V.K. Deshpande, Dean, JNMC and Professor department of Physiology. I have been inspired by his meticulousness, his attention to detail and his energetic application to any problem. I value his concern and support at all times, good and bad. Among the many blessings that have come into my life as a result of his teachings, is an ever-deepening sensitivity to the vibrations of words. Some special words of gratitude go to Dr D.A. Biswas, Professor and head, department of Physiology who have always been a major source of support when things would get a bit discouraging. I have learnt several good things from her and highly indebted to her. Her...