Zinc is one of the most important trace elements that is required for proper growth and health. Being a cofactor of over 200 enzymes and a structural protein in a large number of zinc finger proteins, zinc serves a wide range of roles in human body. In our study Zinc level was found to be significantly decreased in febrile seizures in all previous as well as in present study. Since zinc levels were also found to be significantly low in patients with septic meningitis and cerebral malaria so better response may be expected if we supplement zinc preparation while continuing other treatment in all these diseases.